Carbaryl

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Carbaryl
IUPAC name	1-naphthyl methylcarbamate
Other names	Sevin
Identifiers
CAS number	63-25-2
SMILES	CNC(OC2=CC=CC1=CC=CC=C12)=O
Properties
Molecular formula	C12H11NO2
Molar mass	201.221 g/mol
Appearance	Colorless crystalline solid
Melting point	142 °C
Hazards
EU classification	Carc. Cat. 3 Harmful (Xn) Dangerous for the environment (N)
R-phrases	R22, R40, R50
S-phrases	(S2), S22, S24, S36/37, S46, S61
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references

Carbaryl (1-naphthyl methylcarbamate) is a chemical in the carbamate family used chiefly as an insecticide. It is a colorless white crystalline solid commonly sold under the brand name Sevin, a trademark of the Bayer Company. Union Carbide discovered carbaryl and introduced it commercially in 1958. Bayer purchased Aventis CropScience in 2002, a company that included Union Carbide pesticide operations. It remains the third-most-utilized insecticide in the United States for home gardens, commercial agriculture, and forestry and rangeland protection.

Carbaryl is a cholinesterase inhibitor and is toxic to humans. It is classified as a likely human carcinogen by the United States Environmental Protection Agency (EPA.)^[1] It kills various beneficial insect and crustacean species along with intended pest victims, so care must be taken when spraying where beneficial nontarget species are present. Carbaryl is acutely toxic to honeybees, destroying colonies of bees foraging in an area where the chemical has been applied.

Oral LD₅₀:

• 250 mg/kg to 850 mg/kg for rats
• 100 mg/kg to 650 mg/kg for mice

When ingested by people it is metabolized rapidly and excreted in the urine.

Carbaryl is illegal in several countries, including the United Kingdom, Austria, Denmark, Sweden, Germany and Angola.^[2]

[edit] References

1. ^ Interim Reregistration Eligibility Decision for Carbaryl, U.S. EPA, June 2003.
2. ^ Carbaryl Insecticide Hazard Data

[edit] External links

• Carbaryl Technical Fact Sheet - National Pesticide Information Center
• Carbaryl General Fact Sheet - National Pesticide Information Center
• Carbaryl Pesticide Information Profile - Extension Toxicology Network
• Cholinesterase Inhibition - Extension Toxicology Network
• Sevin facts and controversies
• EPA info
• EPA factsheet
• IPCS (WHO) Health and Safety Guide
• Environmental Health Criteria - WHO
• Exclusive Chemistry Ltd - routes of Sevin synthesis